Bone mass measurements and risk of fracture in Caucasian women: a review of findings from prospective studies.

TitleBone mass measurements and risk of fracture in Caucasian women: a review of findings from prospective studies.
Publication TypeJournal Article
Year of Publication1995
AuthorsCummings SR, Black D
JournalThe American journal of medicine
Volume98
Issue2A
Pagination24S-28S
Date Published1995 Feb 27
ISSN0002-9343
KeywordsAbsorptiometry, Photon, Age Factors, Aged, Aged, 80 and over, Bone Density, European Continental Ancestry Group, Female, Fractures, Bone, Humans, Predictive Value of Tests, Prospective Studies, Risk Factors
Abstract

Prospective studies have shown that bone mass, measured by any method and at any site, is inversely related to a woman's risk of fracture. Most types of fractures are more frequent in women with low bone mass. Bone mineral density measured in the proximal femur appears to have a stronger relationship to risk of hip fracture than bone density measured in other sites. On the other hand, measurement of bone mass in the spine does not appear to be substantially superior to measurements of bone mass in other sites. Even after age 80, bone mass measurements have a strong predictive value for most types of fracture. A woman's lifetime risk of hip fracture can be estimated from bone mass measurements made in the perimenopausal period. Although an individual's level of bone mass may vary from site to site, the incremental value of measuring bone mass in more than one site is not certain. Bone mass measurements, perhaps in combination with other risk factors for fracture, help define individuals with a high risk of fracture who stand to benefit most from efforts to prevent fractures.

Alternate JournalAm. J. Med.
PubMed ID7709929
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