Nid Year Notes All terms
67 1 2004


Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, and the second most common cause of mortality in children aged 1-14 years. Recent research has established that the disease can originate in utero, and thus maternal diet may be an important risk factor for ALL. Dietary carotenoids and glutathione appear to be important contributors to this effect.

83 2 2002

21,454 male participants enrolled in the U.S. Physicians’ Health Study, followed for an average of 17 years. Most dramatic relationship between survival with any food was nut consumption.

Compared with men who rarely or never consumed nuts, those who consumed nuts 2 or more times per week had a 47% lower risk (nearly half the risk) of sudden cardiac death and a 30% lower risk of total coronary heart disease death. (70% of risk for total coronary heart disease).

Nuts and seeds had anti-arrhythmic and anti-seizure effect associated with 60% reduction in sudden cardiac death.

This pattern of benefit on coronary heart disease end points suggests that at least part of the effect of nut consumption on sudden cardiac death may be due to a reduction in fatal ventricular arrhythmias. "consumption of nuts powerfully reduces the chance of having a life-threatening cardiac arrhythmia called ventricular fibrillation or ventricular tachycardia. (People who have heart disease do not always die of heart attacks; they die of an irregular heartbeat that prevents the heart from pumping properly.) Removing nuts and seeds from one’s diet may actually increase the risk of one of these fatal rhythm disturbances."

DPYCCH01, Duplicate, Getaway2010, important, Ti Sano 2013, NET, Disease-Proof Your Child
314 3 2001

A deficiency of any of the micronutrients: folic acid, Vitamin B12, Vitamin B6, niacin, Vitamin C, Vitamin E, iron, or zinc, mimics radiation in damaging DNA by causing single- and double-strand breaks, oxidative lesions, or both.

NET, Disease-Proof Your Child
596 4 2004

7 - 8% reduction in mortality for every 20 gram increase in daily legume intake. (20 gms is about 3/4 of an ounce)

Fall Weekend Immersion 2011, Getaway2011, Ti Sano 2013, NET
613 5 2005

Baltimore Longitudinal Study of Aging

EatRightAmerica, NET
636 6 1998

3834 subjects (the Boyd Orr Cohort) tracked for 50 years. Least calories consumed in childhood: dramatic reductions in breast, prostate and colon cancer as adults. Each 238 calorie daily increase in consumption increased cancer mortality as an adult by 20%.

Animal studies have shown that energy restriction results in a reduced risk of cancer. Some cancers are more common in taller people, suggesting that the same effect may be important in humans
+ The association between diet in childhood and later cancer was examined on the basis of detailed dietary data collected from a cohort of children in the late 1930s
+ A positive association emerged between childhood energy intake and later cancer (other than cancer related to smoking), once adjustment for socioeconomic variables had been made
+ This evidence for long term effects of early diet confirms the importance of optimal childhood nutrition by implying that higher levels of energy intake in childhood increase the risk of the later development of cancer.

The effect of childhood energy intake on later mortality from cancer was seen only for cancers not related to smoking.

Children who consumed the highest quartile of fruit during childhood had a 38 percent lower occurrence of all cancers as adults

DPYCCH03, Cancer, Getaway2010, NET, Disease-Proof Your Child, ETLChapter1, Eat to Live e1
662 7 2003

Red meat and high-fat dairy foods were each associated with an increased risk of breast cancer.

DPYCCH03, NET, Disease-Proof Your Child
664 8 2002

57% reduction in colon cancer risk among high versus low consumers of ITC, among individuals with both GSTM1 and T1 null genotypes. ITCs from cruciferous vegetables modify risk of colorectal cancer in individuals with low glutathione S-transferases (GST) activity. Glucosinolate degradation products act as anticarcinogens by inducing phase II conjugating enzymes, in particular GSTs.

Getaway2010, NET
678 9 2006
679 10 2006
680 11 2002
CVD, Getaway2010, Getaway2011, NET
681 12 2005
682 13 2005

Cruciferous vegetables contain powerful anti-cancer compounds--sulforaphane, and isothyocyanates--that halt the growth of breast cancer cells

683 14 2005
684 15 2005
685 16 2005
686 17 2004
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688 19 2004
690 20 2003
691 21 2003
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695 24 2000
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697 26 1999
698 27 1998

the quarter of the population that eats the fewest fruits and vegetables has approximately double the cancer rate for most types of cancer when compared to the quarter with the highest intake. Common micronutrient deficiencies are likely to damage DNA by the same mechanism as radiation and many chemicals, appear to be orders of magnitude more important, and should be compared for perspective. Remedying micronutrient deficiencies is likely to lead to a major improvement in health and an increase in longevity at low cost.

DPYCCH01, NET, Disease-Proof Your Child
699 28 2003

NRF-2 proteins are transcription factors that bind to, and active the ARE segments of genes. (These are cellular segments in DNA that produce protein that sucks free radicals out of tissue, more effectively than antioxidant. NRF-2 becomes activated (a normal function) when we eat green vegetables supplying ITCs. When we don't eat cruciferous greens the most important natural defense systems in the cell does not function.

Cancer, Getaway2011, Ti Sano 2013, NET
801 29 1993
802 30 1999
McBride J. Can foods forestall aging? Agricultural Research. 1999;47:14-7.