Nidsort icon Year Notes All terms
83 1 2002

21,454 male participants enrolled in the U.S. Physicians’ Health Study, followed for an average of 17 years. Most dramatic relationship between survival with any food was nut consumption.

Compared with men who rarely or never consumed nuts, those who consumed nuts 2 or more times per week had a 47% lower risk (nearly half the risk) of sudden cardiac death and a 30% lower risk of total coronary heart disease death. (70% of risk for total coronary heart disease).

Nuts and seeds had anti-arrhythmic and anti-seizure effect associated with 60% reduction in sudden cardiac death.

This pattern of benefit on coronary heart disease end points suggests that at least part of the effect of nut consumption on sudden cardiac death may be due to a reduction in fatal ventricular arrhythmias. "consumption of nuts powerfully reduces the chance of having a life-threatening cardiac arrhythmia called ventricular fibrillation or ventricular tachycardia. (People who have heart disease do not always die of heart attacks; they die of an irregular heartbeat that prevents the heart from pumping properly.) Removing nuts and seeds from one’s diet may actually increase the risk of one of these fatal rhythm disturbances."

DPYCCH01, Duplicate, Getaway2010, important, Ti Sano 2013, NET, Disease-Proof Your Child
84 2 1999

frequency of nut consumption has been found to be inversely related to all-cause mortality in several population groups such as whites, blacks, and the elderly. Thus, nut consumption may not only offer protection against IHD, but also increase longevity. In a large, prospective epidemiologic study of Seventh-day Adventists in California, we found that frequency of nut consumption had a substantial and highly significant inverse association with risk of myocardial infarction and death from IHD. The Iowa Women's Health Study also documented an association between nut consumption and decreased risk of IHD.

DPYCCH01, Duplicate, Getaway2010, Ti Sano 2013, Disease-Proof Your Child
310 3 2001

In 2000, we reported that there is no reliable evidence that screening for breast cancer reduces mortality. As we discuss here, a Cochrane review has now confirmed and strengthened our previous findings. The review also shows that breast-cancer mortality is a misleading outcome measure.* Finally, we use data supplemental to those in the Cochrane review to show that screening leads to more aggressive treatment. *(Uncertain causes of death were often ascribed to breast cancer, not to radiation). See also Hughes NS.

Certificate in Plant-based Nutrition, McDougall Lecture, Cancer, Getaway2010
494 4 2001

Elderly women with a high dietary ratio of animal to vegetable protein intake have more rapid femoral neck bone loss and a greater risk of hip fracture than do those with a low ratio. This suggests that an increase in vegetable protein intake and a decrease in animal protein intake may decrease bone loss and the risk of hip fracture. This possibility should be confirmed in other prospective studies and tested in a randomized trial.

ChCh10, Getaway2010, The China Study - Book
569 5 1998

The wheat bran supplement increased fecal bulk. On the resistant starch phases, the mean fecal butyrate:SCFA ratio, which has been suggested to have positive implications for colonic health, was significantly above the low-fiber control

Getaway2010, Getaway2011
570 6 1995

the insulin response curve area was significantly lower in all subjects after amylose consumption. Fasting triglyceride concentrations were significantly lower in subjects who consumed the high-amylose compared with the standard-starch diet.

Getaway2010, Getaway2011
571 7 2006

brachial artery vasodilation tests' intra-vascular inflammation decreases as vegetable portions increase. The risk of CHD was decreased by 4% for each additional portion per day of fruit and vegetable intake and by 7% for fruit intake.

CVD, Getaway2010, Getaway2011
572 8 2006

Meta-analysis and brachial artery tests consistently show that as vegetable portions per day increase, intra-vascular inflammation decreases and elasticity and function improves, reducing heart attack and stroke risk. Best predictor of heart disease and stroke is fruit and vegetable consumption.

Getaway2010, Getaway2011, important
573 9 2001

Those with highest blood levels of lutein had the healthiest blood vessels, with no atherosclerosis. (Lutein an indicator of green vegetable consumption.)

CVD, Getaway2010, Getaway2011
576 10 2003

Offspring study of Framingham heart study. "Urinary markers of oxidative stress found to correlate well with BMI diabetes, blood glucose and heart disease; low micronutrient eating promotes an inflammatory cascade underlying most disease that plague the modern world; excess calories, fat deposition and inadequate phytonutrients create a nation of cardiovascular-diseased individuals."

CVD, Diabetes, Getaway2010, Getaway2011
577 11 2006

Nurses Study: The RR of type 2 diabetes for substituting 1 serving potatoes/d for 1 serving whole grains/d was 1.30 (substituting a whole grain for a serving of potato a day lowered by almost 30 percent)

Diabetes, Getaway2010, Getaway2011, important
578 12 2009

Men consuming 7 or more eggs per week are 58% more likely to develop type-2 diabetes and women are 77% more likely. Men with diabetes who ate any eggs at all were twice as likely to die in the 20 year period. The researchers are not sure which component of the egg is to blame; however suggestive evidence was present for increased risk of heart attack and stroke.

Diabetes, Getaway2010, Getaway2011, Ti Sano 2013
595 13 1994
Baron S, Rinsky R. NIOSH mortality study of NFL football players: 1959-1988. Cincinnati, OH: Centers for Disease Control, National Institute for Occupational Safety and Health. 1994:88-085.

Mortality study of 6,848 professional football players. Large football players -> twice the risk of early cardiac death (half dead before age 50.) 10 of 600 athletes on the 1964 East German Olympic Team is alive today. Players with largest BMI (muscle) had 6x the early death compared with those with the lowest BMI.

Fall Weekend Immersion 2011, Getaway2010, Getaway2011, Ti Sano 2013
599 14 2008

Cruciferous vegetable (Chinese cabbage, bok choy, turnips) intake consistent with high isothiocyanate exposure may reduce breast cancer risk. Cruciferous vegetable intake also may ameliorate the effects of the GSTP1 genotype (which predisposes people to breast cancer). Subjects reporting greater turnip and Chinese cabbage intakes had a significantly lower postmenopausal breast cancer risk (half as much cancer). Women with the GSTP1 Val/Val genotype and low cruciferous vegetable intake had a breast cancer risk 1.74-fold that of women with the Ile/Ile or Ile/Val genotype. This effect of low cruciferous vegetable intake and the Val/Val genotype was seen predominantly among premenopausal women.

Half the cancer with higher intake.

Cancer, Getaway2010, Getaway2011
601 15 2009

Intake of mushrooms decreased the risk of breast cancer by 64%. Mushrooms are aromatase inhibitors, which detoxify estrogens.

Getaway2010, Getaway2011, Getaway2012, Ti Sano 2013, VegSource Healthy Lifestyle Expo 2009
604 16 2009

higher fish intake and DHA levels decrease breast cancer incidence by 50%?

Cancer, Getaway2010, Getaway2011
605 17 2006

71 countries studied
Increase Risk: Animal food, animal fat, milk, sugar, alcohol, stimulants;
Decrease Risk: sunshine, onions, soybeans, beans, (green veggies)

DPYCCH01, Getaway2010, Getaway2011, Getaway2012, Ti Sano 2013, Disease-Proof Your Child
606 18 2002

Frequent consumption of tomato products is associated with a lower risk of prostate cancer. The magnitude of the association is moderate and could easily be missed in a small study.

Cancer, Getaway2010, Getaway2011, Getaway2012
607 19 2008

Will men adhere to tomato intervention? Prostate cancer patients will consume diets rich in tomato products and soy with excellent compliance and bioavailability of phytochemicals.

Cancer, Getaway2010, Getaway2011, Getaway2012, Ti Sano 2013
629 20 2008

78% increased risk of all-cause mortality in the lowest quartile. Also, too much Vitamin D raises risk. (50% reduced risk of breast cancer. Dr. Fuhrman recommends 35 - 45 range. 2000/Day RDI is 400.)

Cancer, Getaway2010, Getaway2011
636 21 1998

3834 subjects (the Boyd Orr Cohort) tracked for 50 years. Least calories consumed in childhood: dramatic reductions in breast, prostate and colon cancer as adults. Each 238 calorie daily increase in consumption increased cancer mortality as an adult by 20%.

Animal studies have shown that energy restriction results in a reduced risk of cancer. Some cancers are more common in taller people, suggesting that the same effect may be important in humans
+ The association between diet in childhood and later cancer was examined on the basis of detailed dietary data collected from a cohort of children in the late 1930s
+ A positive association emerged between childhood energy intake and later cancer (other than cancer related to smoking), once adjustment for socioeconomic variables had been made
+ This evidence for long term effects of early diet confirms the importance of optimal childhood nutrition by implying that higher levels of energy intake in childhood increase the risk of the later development of cancer.

The effect of childhood energy intake on later mortality from cancer was seen only for cancers not related to smoking.

Children who consumed the highest quartile of fruit during childhood had a 38 percent lower occurrence of all cancers as adults

DPYCCH03, Cancer, Getaway2010, NET, Disease-Proof Your Child, ETLChapter1, Eat to Live e1
663 22 1996

Review of 206 human studies and 22 animal studies: raw vegetables have the most consistent and powerful association with the reduction of cancers of all types, including stomach, pancreas, colon, and breast

DPYCCH02, Eat to Live E2, Cancer, ETLChapter6, Getaway2010, VegSource Healthy Lifestyle Expo 2009, Disease-Proof Your Child
664 23 2002

57% reduction in colon cancer risk among high versus low consumers of ITC, among individuals with both GSTM1 and T1 null genotypes. ITCs from cruciferous vegetables modify risk of colorectal cancer in individuals with low glutathione S-transferases (GST) activity. Glucosinolate degradation products act as anticarcinogens by inducing phase II conjugating enzymes, in particular GSTs.

Getaway2010, NET
665 24 2008

case-controlled study of 4000+ women: strong association (25 - 30% reduction) between soy food and reduced incidence of the most common types of breast cancer: ER+/PR+/HER2- tumor

Cancer, Getaway2010
667 25 2005

Red meat, pork, processed meats demonstrated 68% increase in risk of cancer (comparing highest to lowest quintile)

Cancer, Getaway2010, VegSource Healthy Lifestyle Expo 2009
668 26 2009

Higher intake of saturated fat from dairy and meat more than doubled risk of pancreatic cancer

Cancer, Getaway2010, VegSource Healthy Lifestyle Expo 2009
669 27 2007

Chronic inflammation increases all causes of death. High white blood cell counts are a better predictive association than other markers. More than double the risk for breast cancer with higher numbers.

Cancer, Getaway2010, VegSource Healthy Lifestyle Expo 2009
670 28 2007

Low-carb/high protein increased CRP by 25%
High-carb/lo-fat reduced serum CRP by 43%

Cancer, Getaway2010, VegSource Healthy Lifestyle Expo 2009
672 29 2008

Hospitalizations for heart failure increased 23% for those with higher intake of eggs. 16% higher risk of hospitalization for higher intake of daily fat

CVD, eggs, Getaway2010, Getaway2011, important
673 30 2009

Greens needed to activate NRF2 proteins (transcription factors), which prevents plaque adhesion--makes slippery. highest level of blood lutein have healthiest blood vessels with no atherosclerosis; (lutein level mostly a research tool.)

CVD, Getaway2010, Getaway2011, important, Ti Sano 2013
674 31 2007

Cochrane review of 68 randomized trials. Vitamin A supplementation (20,000 IU) showed an average of 16% increase mortality risk. Beta carotene increased mortality risk by 7% (mean 3 years). No significant increased or decreased mortality from Vitamin C and selenium

Cancer, Getaway2010
675 32 1998

For every 1-mg increase in daily intake of retinol, risk for hip fracture increased by 68%. For intake greater than 1.5 mg/d compared with intake less than 0.5 mg/d, bone mineral density was reduced by 10% at the femoral neck, 14% at the lumbar spine, and 6% for the total body, and risk for hip fracture was doubled.

Getaway2010, Osteoporosis, Supplements, DPYCCH05, Disease-Proof Your Child
680 33 2002
CVD, Getaway2010, Getaway2011, NET
689 34 2004

Regardless of ethnic group or energy adjustment, high and frequent vegetable consumption (particularly dark green vegetables) was protective, consistent with 20-50% reductions in risk. In Caucasians, high refined carbohydrate and red meat consumption (amount and frequency) was associated with a statistically significant 2-fold increased risk in non-energy adjusted models. In African-Americans, frequent intake of dairy foods was associated with a doubling in risk (OR = 1.9, 95% CI = 1.1-3.4) in non-energy-adjusted models, whereas frequent fruit consumption correlated with a non-significant 30% lower risk.

DPYCCH03, Getaway2010, Ti Sano 2013, Disease-Proof Your Child
700 35 2008

Caloric restriction resulting in lower IGF-1 levels dramatically extends life in rodents and other animals. Lower IGF-1 levels protect against cancer and slow aging. Protein intake is the key determinant of IGF-1 levels in humans.

701 36 2004

Adherence to the guidelines for fruit and vegetable intake was associated with lower cancer risk. Besides quantity, variety in intake is also of importance.

702 37 2008

Fosamax increased hip fractures 84%

703 38 2008

Low-energy fractures of the femoral shaft with a simple, transverse pattern and hypertrophy of the diaphyseal cortex are associated with alendronate use. This may result from propagation of a stress fracture whose repair is retarded by diminished osteoclast activity and impaired microdamage repair resulting from its prolonged use.

704 39 2005
LOGUE A. Acid Suppression Raises Hip Fracture Risk. Family Practice News. 2005;35:53.

The use of Proton Pump Inhibitors in older women, and perhaps older men with low calcium intake, may be associated with a modest increased risk of non-spine fracture. (Nearly twice the fractures)

705 40 2009

insufficient vitamin D causes cartilage loss in knee joints, and worsening osteoarthritis. 880 men and women, ages 51 -79.

706 41 2003
707 42 2005

protein intakes for elderly women above current recommendations may be necessary to optimize bone mass.

708 43 2001

15 studies reviewed: the consumption of olive oil was associated with a 7% increase in the risk of coronary heart disease.

Olive oil cannot be considered more cardioprotective than other unsaturated vegetable oils as judged from its effects on blood lipids, raising LDL, and triglycerides

709 44 1998

Oils with a high PUFA n-6 content and high n-6/n-3 ratio in dietary fats are atherogenic and diabetogenic. The newer "heart-friendly" oils like sunflower or safflower oils possess this undesirable PUFA content and there are numerous research data now available to indicate that the sole use or excess intake of these newer vegetable oils are actually detrimental to health and switching to a combination of different types of fats including the traditional cooking fats like ghee, coconut oil and mustard oil would actually reduce the risk of dyslipidaemias, AHD and Type-2 DM.

710 45 2005

Review of 23 interventional trials show dramatic reduction in all-cause mortality by those consuming nuts and seeds

Consumption of approximately 50-100 g (approximately 1.5-3.5 servings) of nuts 5 or more times/wk as part of a heart-healthy diet with total fat content (high in mono- and/or polyunsaturated fatty acids) of approximately 35% of Energy may significantly decrease total cholesterol and LDL cholesterol (especially small dense LDL) in normo- and hyperlipidemic individuals.

Sudden Cardiac Death (the most common cause of death in people with no known heart disease) constitutes almost 40 percent of all heart disease deaths

The most proven and effective intervention to reducing risk of sudden cardiac death is the regular consumption of seeds and nuts in the diet.

the magnitude of the cholesterol-lowering effect was shown to be 25% greater than would be predicted based on the fatty acid profiles of the test diets studied (2). Therefore, the possible mechanisms whereby nuts may improve lipid profiles do not rely exclusively on the beneficial action of unsaturated fatty acids (PUFA and MUFA) but may include the effects of fiber, micronutrients such as vitamin E and C, folic acid, copper, magnesium, plant protein (e.g., arginine), plant sterols, and phenolic components.

"Large drop in LDL cholesterol, especially the most dangerous small LDL. Raise LDL. Reduce CRP and plaque adhesion molecules. Increase arginine. Restore vascular elasticity."

- increase arginine
- restore vascular elasticity
- recue c-reactive protein and plaque adhesion
- raise hdl
- large drop in ldl especially most dangerous type

Getaway2010, Ti Sano 2013
711 46 2000

A low-fat high-carbohydrate diet (15% fat, 65% CHO, 20% protein of total calories), typically eaten by athletes, Increases:
inflammatory cytokines, and free radicals
athletic endurance, anti-inflammatory mediators, immune factors (by half; natural killer cells are needed to fight infection), depresses antioxidants, and negatively affects blood lipoprotein ratios.

712 47 2004

Substituting walnuts for monounsaturated fat in a Mediterranean diet improves endothelium-dependent vasodilation in hypercholesterolemic subjects. This finding might explain the cardioprotective effect of nut intake beyond cholesterol lowering.

713 48 2004

More than 10 times as much of certain nutrients (alpha-carotene, beta-carotene, and lycopene) are absorbed from vegetables with nuts or seeds are consumed with the meal

748 49 2007
749 50 2008

n-3 PUFA dietary intake exerts neuroprotective actions in an animal model of Parkinsonism

750 51 2006

DHA can reduce the severity or delay the development of levodopa-induced dyskinesias (LIDs) in a nonhuman primate (monkey) model of Parkinson's disease.

751 52 2009

This study found no association between grapefruit intake and breast cancer

Cancer, Getaway2010
752 53 2009

1 in 2000 undergoing mammograms have lifespan enhanced from detection and treatment. 10 in 2000 are hurt in some way from mammograms and subsequent treatment. 5 in 2000 with BRCA1 or BRCA2 genes for breast cancer have radiation induced increased mortality from mammograms

Cancer, Getaway2010
753 54 2004

Radiation after lumpectomy shows no benefit in mortality either from breast cancer or any other cause. (See also Cochrane review: )

754 55 2002

Results agree with previous studies in favor of an increased risk of lung cancer after radiation therapy for breast cancer.

Cancer, Getaway2010
755 56 2001

No survival benefit for postmenopausal, estrogen receptor (ER)-positive women with breast cancr using adjuvant cyclophosphamide/methotrexate/5-fluorouracil (CMF)-type chemotherapy. 5.5% had longer disease-free life.

Cancer, Getaway2010
756 57 2003

Kaiser Health Foundation study: Medicare enrollees in higher-spending regions receive more care than those in lower-spending regions but do not have better health outcomes or satisfaction with care. (Dr. Fuhrman notes: "a third of medical spending is devoted to services that don't improve health or the quality of care, and may make things worse")

Cancer, Getaway2010, Super Immunity
757 58 2008

PSA screenings and medical interventions for prostate cancer not shown to extend lifespan for men

Cancer, Getaway2010
758 59 2005
Cancer, Getaway2010
759 60 2010

30% reduction in prostate cancer occurrence with those in the highest quartile of DHA intake. among those diagnosed at an early stage, men with the highest zinc intake (15 mg or more) were 74% less likely to die of prostate cancer. Zinc is low on a vegan diet, with low bioavailability. Zinc supplementation and half the mortality rate.

Cancer, Getaway2010, Getaway2011
760 61 2000

Supplementation of zinc corrects central and peripheral immune defects, resulting in prolonged survival and decreased mortality (50%) from infections and tumors, especially during middle age.

761 62 2008

zinc reduces the risk of cancer; iron increases the risk

Cancer, Getaway2010
762 63 1999
Cancer, Getaway2010
763 64 2002
Cancer, Getaway2010
764 65 2005

% risk reduction 0 up to 0.155 mg day
0 – 0.155 0%
0.155-0.227 6%
0.227-0.318 49%
> 0.318 71%

Dietary flaxseed has the potential to reduce tumor growth in patients with breast cancer. double-blind placebo-controlled RCT. After being dx'd with breast cancer, women at a control or flax-containing muffin daily (32-39 days) significant apoptosis. More than 1/3 mg lignan had 71% risk of reduction in breast cancer mortality. 1 teaspoon has 7 mg lignans.

Getaway2010, Getaway2012
765 66 2009

No fewer heart attacks or deaths with stent placements!